Publications by authors named "R M Gunasekera"

Background: Children with chronic diseases have been reported to participate in less regular physical activity (PA) than peers without chronic diseases; and less than recommended in guidelines. Sheffield Children's Foundation Trust (SCFT) is an Active Hospitals pilot site, exploring options to facilitate PA for all children. One option is collaboration with Junior Parkrun: a free, weekly 2 km running event for children.

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Since the outset of the COVID-19 pandemic, the global healthcare community has faced the challenge of understanding and addressing the ongoing and multi-faceted SARS-CoV-2 infection outcomes. As millions of individuals worldwide continue to navigate the complexities of post-hospitalization recovery, reinfection rates, and the increasing prevalence of Long-COVID symptoms, comprehensive COVID-19 rehabilitation strategies are greatly needed. Previous studies have highlighted the potential synergy between exercise and nutrition, suggesting that their integration into patient rehabilitation programs may yield improved clinical outcomes for survivors of COVID-19.

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With the numerous genomes sequenced today, it has been revealed that a noteworthy percentage of genes in a given taxon of organisms in the phylogenetic tree of life do not have orthologous sequences in other taxa. These sequences are commonly referred to as "orphans" or "ORFans" if found as single occurrences in a single species or as "taxonomically restricted genes" (TRGs) when found at higher taxonomic levels. Quantitative and collective studies of these genes are necessary for understanding their biological origins.

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Article Synopsis
  • The study examines the population structure of Bull Sharks globally, revealing reproductive isolation among different ocean basins and distinct island populations, such as those in Japan and Fiji.
  • Through advanced DNA analysis, researchers found that Bull Sharks use shallow coastal waters for dispersal, while geographical barriers limit gene flow, which impacts their conservation.
  • The findings highlight the vulnerability of local Bull Shark populations to overfishing, particularly among females that return to specific breeding areas, emphasizing the need for targeted management strategies to prevent local declines.
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