Publications by authors named "R M Gueant-Rodriguez"
: Vitamin B12 deficiency can cause variable symptoms, which may be irreversible if not diagnosed and treated in a timely manner. We aimed to develop a widely accepted expert consensus to guide the practice of diagnosing and treating B12 deficiency. : We conducted a scoping review of the literature published in PubMed since January 2003.
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- Anaphylaxis is a severe allergic reaction initiated by allergens activating B-cells, but existing understanding of its mechanisms is incomplete, prompting a review of proteomic and metabolomic studies to identify new biomarkers.
- A systematic search identified 12 relevant studies from 137 publications, which showed variations in protein expression related to neutrophil activation and platelet degranulation, along with common metabolites like arachidonic acid.
- The findings suggest that neutrophils and platelets play a greater role in anaphylaxis than previously thought, but require further research with larger human study samples to validate and potentially develop new diagnostic biomarkers.