[The efficiency of modernmethods of laboratory diagnosis in the evaluation of various forms of hemorrhagic fever with renal syndrome caused by the Puumala hantavirus (PUUV).].

We've conducted the analysis of both traditional and new methods of laboratory diagnosis to estimate the severity and damage of target organs during Hemorrhagic Fever with Renal Syndrome (HFRS). It was shown that thrombocytopenia corresponds to the severity of the disease and correlates with the severity of renal failure. The level of C-reactive protein reflects the activity of the inflammatory process and correlates with the characteristic laboratory criteria of the disease.

[The diagnostic value of serum alveomucin test in diseases with lungs affection].

The study was organized to determine the diagnostic value of concentration of blood serum alveo-mucin as a marker of lesion of lung tissue in patients with community-acquired pneumonia and hemorrhagic fever with renal syndrome. The sampling included 86 patients with community-acquired pneumonia and 97 patients with hemorrhagic fever with renal syndrome. The patients with community-acquired pneumonia were divided in three groups according severity of disease course: slight form, medium-severe form and severe form of disease.

[Clinical and morphological parallels in lung lesions associated with hemorrhagic fever with renal syndrome].

The authors report the results of clinical examination of the respiratory, organs of 97 patients with hemorrhagic fever and renal syndrome (HFRS) with confirmed Puumala serotype. Retrospective analysis of 16 fatal cases is presented. It is shown that patients with moderately severe and severe forms of the disease exhibit early clinical and X-ray signs of pulmonary lesions and respiratory insufficiency Some of them suffer acute respiratory distress syndrome confirmed by morphological findings at autopsy.

[Cardiopulmonary syndrome in hantavirus infection (an overview)].

The article provides an overview of domestic and foreign literature on modern aspects of hantavirus infection. Hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome have a high epidemiological significance for Russia's Armed Forces and the armies of many foreign countries. Current knowledge of the various manifestations of the disease contribute to the improvement of diagnosis and timely delivery of medical and preventive measures.

[The diagnostic significance of alveomucin in patients with hemorrhagic fever with renal syndrome].

The article considers the results of analysis of serum alveomucin levels in 97 patients with hemorrhagic fever with renal syndrome depending on the form and period of disease. It is demonstrated that in patients with hemorrhagic fever with renal syndrome and clinical radiologic symptoms of lung affection already in initial period of disease the level of serum alveomucin is reliably higher than in the control group and the group of patients with hemorrhagic fever with renal syndrome and without lung affection. The correlation analysis revealed the reverse dependence between the level of alveomucin and arterial blood saturation with oxygen in patients with hemorrhagic fever with renal syndrome and disease form of medium severity.