Publications by authors named "R M Davie"

Article Synopsis
  • The study examined complications following outpatient total hip arthroplasty (THA) by analyzing data from the National Surgical Quality Improvement Program database between 2012 and 2019, focusing on the timing of such complications.
  • It found that for various complications, the median days of diagnosis post-surgery varied, with some issues like stroke and myocardial infarction occurring earlier compared to infections and readmissions.
  • While outpatients showed a lower risk for certain complications like readmission and surgical site infections, both outpatient and inpatient procedures had similar timing for complications, suggesting a need for earlier diagnostic testing in outpatient cases during identified risk periods.
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Objectives: A tibial tubercle-trochlear groove (TT-TG) distance of 20 millimeters (mm) is typically used when determining whether tibial tubercle medialization is performed for the surgical treatment of patellar instability. Without knowledge of how the variability of an individual's TT-TG distance is influenced by through-the-knee femorotibial rotation, the use of a specific TT-TG distance during preoperative planning for patellar instability may lead to incorrect decisions on the use of tibial tubercle medialization. We hypothesized that knee joint internal/external (IE) rotation is related to the TT-TG distance.

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Hereditary angioedema (HAE), a rare genetic disorder, is associated with uncontrolled plasma kallikrein (PKa) enzyme activity leading to the generation of bradykinin swelling in subcutaneous and submucosal membranes in various locations of the body. Herein, we describe a series of potent α-amidobenzylboronates as potential covalent inhibitors of PKa. These compounds exhibited time-dependent inhibition of PKa (compound IC 66 nM at 1 min, 70 pM at 24 h).

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Purpose: There are various anatomic risk factors for patellofemoral instability (PFI) that help guide surgical treatment, including the tibial tubercle to trochlear groove (TT-TG) distance. However, no study has analysed the temporal changes in TT-TG prior to surgical intervention. This study sought to understand the variations in TT-TG over time for pediatric patients suffering from PFI prior to surgical intervention.

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Background: Retinal tears (RT) from posterior vitreous detachment (PVD) are an important and treatable cause of rhegmatogenous retinal detachment (RRD). Better understanding of the risk of RT from PVD will help plan urgent eye care.

Methods: Prospective observational case series over two years.

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