Publications by authors named "R M Cabrera"
Folic acid (FA) is well known to prevent neural tube defects (NTDs), but we do not know why many human NTD cases still remain refractory to FA supplementation. Here, we investigate how the DNA demethylase TET1 interacts with maternal FA status to regulate mouse embryonic brain development. We determined that cranial NTDs display higher penetrance in non-inbred than in inbred Tet1 embryos and are resistant to FA supplementation across strains.
View Article and Find Full Text PDFSelf-Determination Theory (SDT) maintains that the satisfaction of the basic psychological needs for , , and is associated with optimal individual functioning, including in the workplace. A self-report instrument, the Work-related Basic Need Satisfaction scale (W-BNS), has previously been developed and validated in Dutch and Italian. We aimed to validate an English version of the W-BNS.
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- - This study investigates the impact of direct-acting antiviral (DAA) treatment on mortality rates in Medicare beneficiaries with hepatitis C-related liver cancer (HCC).
- - Researchers reviewed data from nearly 20,000 adults and found that those receiving DAA therapy had significantly lower mortality rates compared to those who did not receive any HCV treatment.
- - The findings suggest that DAA treatment improves survival for patients with HCV-related HCC, regardless of cancer stage or treatment type, indicating it should be offered to these patients.
Objective: The aim of the study was to describe laparoscopic ultrasound (LUS) to guide microwave ablation (MWA) of hepatocellular carcinoma (HCC) in a dog.
Animals: A 13-year-old female spayed Husky.
Study Design: Case report.
The genetic basis of nonsyndromic familial nonmedullary thyroid carcinoma (FNMTC) is still poorly understood, as the susceptibility genes identified so far only account for a small percentage of the genetic burden. Recently, germline mutations in DNA repair-related genes have been reported in cases with thyroid cancer. In order to clarify the genetic basis of FNMTC, 94 genes involved in hereditary cancer predisposition, including DNA repair genes, were analyzed in 48 probands from FNMTC families, through targeted next-generation sequencing (NGS).
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