Publications by authors named "R M Bottomley"

Blue spaces (water bodies) may promote positive mental and physical health through opportunities for relaxation, recreation, and social connections. However, we know little about the nature and extent of everyday exposure to blue spaces, particularly in settings outside the home or among children, nor whether exposure varies by individual or household characteristics. Wearable cameras offer a novel, reliable method for blue space exposure measurement.

View Article and Find Full Text PDF

The principal allergen in cow's milk is beta-lactoglobulin (beta-Lg) which is normally found as equal mixtures of the A and B genetic variants in pooled milk. The A and B variants were purified in large amounts and fed to guinea pigs. After 15 days, circulating immunoglobulins IgG1 and IgG2 to the milk proteins were detected, with a somewhat higher response to beta-Lg A than B.

View Article and Find Full Text PDF

Fifty-six patients with squamous cell carcinoma of the head and neck were treated with the combination of vincristine, bleomycin, and methotrexate (VBM) on an every 2-week schedule. The overall CR + PR rate was 20%. Median response duration was 10 weeks.

View Article and Find Full Text PDF