Reference values of indices of spontaneous baroreceptor reflex sensitivity.

Spontaneous baroreceptor reflex sensitivity (BRS) is a well established method for determining baroreflex function, which can be used to assess the potential impact on survival after myocardial infarction, to detect autonomic dysfunction in diabetic patients and in human essential hypertension. The assessment of impaired spontaneous baroreflex function in individual patients contains important clinical information, but age-dependent reference values are still lacking. In the present study we evaluated spontaneous BRS in healthy human controls to determine reference values as a function of age.

Impaired activation of the baroreflex loop as early sign of sympathetic damage in diabetics with normal heart rate variability at rest.

The objective of the study was to define the impairment of sympathovagal balance in patients with diabetes mellitus (DM) and coronary heart disease (CHD) compared to healthy controls (HC) showing similar heart rate variability (HRV) at supine rest. 88 DM (41 m, 47 f; age 62 +/- 1 years; BMI 27.1 +/- 1.

Systolic time intervals after a seven-day orbital flight.

Heart rate, systolic time intervals (pre-ejection period, left ventricular ejection time , ejection friction, stroke volume and QT interval of two cosmonauts (Leonid Popov--L.P. and Dumitru Prunariu--D.

Systolic time intervals after a seven-day orbital flight.

Heart rate (HR), systolic time intervals (STI) (pre-ejection period--PEP, left ventricular ejection time--LVET, PEP/LVET ratio indirect ejection fraction--EF, stroke volume--SV and QT interval of two cosmonauts (Leonid Popov--LP and Dumitru Prunariu--DP), were studied before, during and after an ergometric bicyle exercise test performed before and after the seven-day Soviet-Romanian orbital flight on the Soyuz 40--Saliut 6 Complex in May 1981. To this purpose one precordial electrocardiogram (Ecg) and the ear densitogram (Den) were recorded simultaneously. The method used permitted clear recordings even during exercise.