Publications by authors named "R M Ayabe"
Background: The oncologic significance of specific KRAS point mutations for patients with colorectal liver metastases (CLM) is uncertain. This study aimed to assess the prognostic impact of KRAS point mutations on patients who underwent surgery for CLM.
Methods: Patients who underwent curative-intent surgery for CLM from 2001 to 2020 were selected for the study.
Background: Carcinoembryonic antigen (CEA) levels may vary with administration and discontinuation of pre-hepatectomy chemotherapy in patients undergoing resection of colorectal cancer liver metastases (CLM). The prognostic significance of these changes, termed CEA dynamics, is unclear.
Patients And Methods: Consecutive patients undergoing hepatectomy for CLM (2001-2021) at a comprehensive cancer center were included.
Article Synopsis
- - The study reviews current immunotherapy approaches for small bowel neuroendocrine tumors (SBNET) and explores future avenues for better treatment responses
- - Key treatments like somatostatin analogs and mTOR inhibitors are essential, while new applications of peptide receptor radionuclide therapy (PRRT) show promise, though existing immunotherapies have had limited success
- - Increased incidence of SBNET highlights the need for more effective therapies, and further research into the immune microenvironment may uncover new targets for improved patient outcomes
Introduction: Cost-effectiveness of Robotic-assisted hepatectomy compared to the open approach is scrutinized. We compared the costs of robotic versus open hepatectomy at a large cancer center.
Methods: Patients undergoing hepatectomy (1/2019-2/2022) were collected from a prospectively maintained database and 1:1 propensity score matched for 61 robotic and 61 open hepatectomy patients by complexity, tumor diagnosis, and age >65.