Publications by authors named "R M Ahmed"
Article Synopsis
- Proteoglycans like biglycan (Bgn) and decorin (Dcn) are crucial for bone health, primarily by attracting water through their unique structures, but their specific functions are not fully understood.
- Research using knockout mouse models revealed that Bgn deficiency leads to significant bone loss and reduced resilience, while Dcn appears to have a less pronounced impact, although it compensates when Bgn is absent.
- Both Bgn and Dcn are essential for important signaling pathways in bone maintenance, with Bgn playing a dominant role in preserving bone structure and hydration levels.
Article Synopsis
- Gastrointestinal (GI) barrier dysfunction is a critical early indicator of multiple complex diseases, but current testing methods for saccharide molecules used to assess this function are expensive and time-consuming.
- A new one-component system utilizing a naphthyl-pyridine core and boronic acid receptor has been developed for the early detection of saccharide biomarkers like lactulose, which indicates GI barrier issues.
- The innovative design incorporates a scalable 96-well format with gold nanoparticles and combines plasmonics and fluorescence for sensitive lactulose quantification, aiming to create an affordable and portable diagnostic tool for routine GI permeability testing.
Dengue is a mosquito-borne infection that in recent years has become a vital disease of international public health concern. Dengue virus infections and illness when symptomatic, that patients tend to present with a significantly wide variety manifestation. The aim of the study was to gauge liver dysfunction in patients with dengue infections.
View Article and Find Full Text PDFHemoglobin is a common hematological parameter assessed in laboratory and also an important tool for clinical management of patients. Reference values being used in most laboratories in our country, have been provided from the established reference values of developed countries. Hemoglobin concentration varies usually due to age, sex, attitude, ethnic origin, dietary habits, socioeconomic status and environmental factor.
View Article and Find Full Text PDFAmbiguous genitalia is a rare disorder where it is unclear whether an infant's external genitals are male or female. This can be attributed to various internal and external etiologies, such as androgen receptor abnormalities, gonadal abnormalities (such as gonadal dysgenesis or Klinefelter syndrome where a male has an extra X chromosome), enzymatic defects, etc. Correction of such atypical genitalia requires a multidisciplinary approach, including but not limited to surgeons and therapists.
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