Publications by authors named "R M Abdul Hadi"
Background: Gene signatures derived from transcriptomic-causal networks offer potential for tailoring clinical care in cancer treatment by identifying predictive and prognostic biomarkers. This study aimed to uncover such signatures in metastatic colorectal cancer (CRC) patients to aid treatment decisions.
Methods: We constructed transcriptomic-causal networks and integrated gene interconnectivity into overall survival (OS) analysis to control for confounding genes.
Introduction: Holmium laser enucleation of the prostate (HoLEP) is known to have a steep learning curve. The top-down technique was introduced to lessen the number of procedures required to master HoLEP. We aimed to present the experiences of two successive clinical fellows with the top-down HoLEP learning curve and compare their performance with the supervisor.
View Article and Find Full Text PDFSince the onset of the COVID-19 pandemic, a variety of diagnostic approaches, including RT-qPCR, RAPID, and LFA, have been adopted, with RT-qPCR emerging as the gold standard. However, a significant challenge in COVID-19 diagnostics is the wide range of symptoms presented by patients, necessitating early and accurate diagnosis for effective management. Although RT-qPCR is a precise molecular technique, it is not immune to false-negative results.
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- This study compares the safety and effectiveness of flexible ureteroscopy (f-URS) and ambulatory tubeless mini-percutaneous nephrolithotomy (mini-PCNL) for treating 1-2 cm lower calyceal renal stones in a randomized controlled trial involving 72 patients.
- Results show that mini-PCNL had a longer operative time but significantly higher stone-free rates (SFR) at both postoperative Day 1 and three months later compared to f-URS.
- Both procedures had similar postoperative complications, but two patients in the f-URS group required re-treatment, highlighting the need to assess the best surgical approach for specific cases.
Article Synopsis
- Endometrial carcinoma (EC) is a prevalent type of gynecological cancer in India, and this study aimed to evaluate how central histopathological reviews impact patient management and outcomes based on data from 75 patients treated between 2013 and 2022.
- The analysis revealed substantial changes in histopathological findings for nearly all patients (96.3%), with significant alterations influencing treatment decisions for 19 of those reviewed.
- Most patients were staged I (64%), with treatments including external beam radiotherapy and brachytherapy, demonstrating the importance of thorough pathology review in improving clinical management and outcomes for EC patients.