Publications by authors named "R M Abdelnaby"
The Role of High-Resolution Ultrasound in the Diagnosis of Nerve Trauma New Perspective: A Preliminary Systematic Review and Meta-Analysis of the Recent Evidence.
J Clin Neurophysiol
November 2024
Article Synopsis
- The localization and prognosis evaluation of peripheral nerve injuries is difficult in acute cases, but high-resolution ultrasound (HRUS) may provide a cost-effective imaging solution.
- A systematic review and meta-analysis of 15 studies demonstrated HRUS's high diagnostic accuracy for traumatic nerve injuries, with sensitivity at 92% and specificity at 86%.
- The findings suggest that HRUS can effectively complement existing diagnostic methods, but further research is needed to explore the ultrasound characteristics of these injuries.
Background/ Aim: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting upper and lower motor neurons, causing progressive atrophy of muscles, hypertonia, and paralysis. This study aimed to evaluate the current evidence and effectiveness of ultrasound in investigating nerve cross-sectional area (CSA) of peripheral nerves, vagus and cervical roots in those with ALS compared with healthy controls and to pool the CSA measurements.
Methods: A systematic search was conducted on Cochrane, Clarivate Web of Science, PubMed, Scopus, and Embase for the mesh terms nerve, ultrasonography, and amyotrophic lateral sclerosis.
Factors associated with the laterality of Cardio-Embolic stroke.
J Stroke Cerebrovasc Dis
December 2023
Objective: Understanding the lateralization factors, including the anatomic and hemodynamic mechanisms, is essential for diagnosing cardio-embolic stroke. This study aims to investigate the elements, for the first time together, that could affect the laterality of stroke.
Methods: We performed a monocentric retrospective case-control study based on prospective registries of acute ischemic stroke patients in the comprehensive stroke center of the RWTH University hospital of Aachen for three years (June 2018-June 2021).
Hepatoprotective effects of linalool against liver ischemia-reperfusion: the role of Nrf2/HO-1/NQO1 and TLR4/RAGE/NFκB pathways.
Eur Rev Med Pharmacol Sci
October 2023
Objective: Hepatic ischemia-reperfusion (H I/R) injury arises due to a temporary obstruction followed by the re-establishment of blood supply to the liver. Linalool (LIN), a main volatile constituent of essential oils in numerous aromatic plant species, exhibited various medicinal and pharmacological actions. This study investigated the protective effect of LIN on the status of H I/R, with the study of the possible mechanisms.
View Article and Find Full Text PDFArticle Synopsis
- A study aimed to determine if serum creatine kinase (CK) levels could help differentiate between epileptic seizures, psychogenic non-epileptic seizures (PNES), and syncope, since detailed reports of these events are often unavailable.
- The results of a cohort study with 202 patients found that CK levels were significantly higher in patients with epileptic seizures 48 hours after the event compared to those with syncope.
- A meta-analysis involving 1,086 patients reinforced these findings, indicating that CK levels were notably higher in epileptic seizures compared to PNES and syncope, thus suggesting CK could be a useful diagnostic marker.