The influence of orthodontist change on treatment duration and outcomes in patients treated with Clark's twin block appliance followed by non-extraction fixed mechanotherapy - a retrospective cohort study.

Background: Post-graduate resident turnover in public and teaching hospital orthodontic clinics often leads to challenges in maintaining the same level of efficacy when a care provider changes during orthodontic treatment. This retrospective cohort study aimed to compare the duration and quality of treatment outcomes between two patient groups: the transfer group, who underwent orthodontic care from multiple residents, and the non-transfer group, whose entire treatment was overseen by a single resident.

Methods: Sixty-six patients were enrolled and equally divided into transfer and non-transfer groups.

The possible anti-tumor effects of regulatory T cells plasticity / IL-35 in the tumor microenvironment of the major three cancer types.

T lymphocytes are among the immunological cells that make up the tumor microenvironment (TME), and they are essential in the growth of tumors and anti-tumor reactions. Regulatory T cells (Treg cells) are a subset of CD4+ T cells in the immune system that suppress the immune system. They are distinguished by their expression of the master transcription factor forkhead box protein P3 (FOXP3).

Treatment options for chronic hypotony: a scoping review protocol.

Introduction: Chronic ocular hypotony (low intraocular pressure (IOP)) is a potentially sight-threatening condition. Although there is some controversy as to what constitutes non-physiological IOP, generally it is accepted as an IOP of 6.5 mm Hg or less, measured on three separate occasions and lasting for at least 3 months.