Assessing the differential responses in normal and inflamed in vitro intestinal models exposed to food contaminants complex mixtures.

The intestinal barrier is crucial for gut health, and its dysfunction can lead to chronic inflammatory conditions. Food contaminants like pesticides, heavy metals, mycotoxins, heterocyclic aromatic amines (HAAs), and polycyclic aromatic hydrocarbons (PAHs) may worsen these conditions. However, research often overlooks the complex interactions between contaminants and the different cells in the intestine.

Innovative extraction methods for non-phthalate plastic additives determination in water using GC and LC coupled to Q-Orbitrap.

This study investigates the presence of non-phthalate plastic additives (NPPAs), emerging contaminants increasingly used as alternatives to hazardous phthalates, in various water sources. To address their potential environmental and health risks, two complementary extraction methods were developed: direct immersion solid-phase microextraction gas chromatography coupled to Q-Orbitrap (DI-SPME-GC-Q-Orbitrap) and salting-out assisted liquid-liquid extraction combined with ultra-high-performance liquid chromatography (SALLE-UHPLC-Q-Orbitrap). The complementary use of these two methods makes it possible to analyse a larger number of analytes, 27 in particular, enabling the detection of 19 and 23 NPPAs by GC and LC, respectively (15 compounds were simultaneously monitored by both techniques), with limits of quantification (LOQs) ranging from 0.

Search for New Resonances Decaying to Pairs of Merged Diphotons in Proton-Proton Collisions at sqrt[s]=13 TeV.

A search is presented for an extended Higgs sector with two new particles, X and ϕ, in the process X→ϕϕ→(γγ)(γγ). Novel neural networks classify events with diphotons that are merged and determine the diphoton masses. The search uses LHC proton-proton collision data at sqrt[s]=13  TeV collected with the CMS detector, corresponding to an integrated luminosity of 138  fb^{-1}.

London Rocket ( L.) as Healthy Green: Bioactive Compounds and Bioactivity of Plants Grown in Wild and Controlled Environments.

London rocket () is a wild green consumed globally, yet its phytochemical composition remains underexplored. In this study, we analyzed the leaves of wild plants and those grown in controlled environments (GCE) with varying electrical conductivities (EC) and light spectra. Plants were assessed for growth, phenolic content, vitamin C, antioxidant activity, glucosinolates, and antiproliferative effects against HT-29 human colorectal cancer cells.