Publications by authors named "R Lopez-Lopez"
Article Synopsis
- Malnutrition is prevalent among older individuals in institutions, severely impacting their quality of life, and is linked to various health-related factors that emerge later in life.
- This study utilized the Mini Nutritional Assessment-Short Form (MNA-SF) and the full MNA to evaluate the nutritional status of 207 institutionalized older adults, revealing that those with cognitive impairment, frailty, dysphagia, low BMI, prolonged institutionalization, and low education are at higher risk of malnutrition.
- Findings indicate that different tests may not consistently identify the same determinants of malnutrition, highlighting the necessity for effective nutritional screening tools to mitigate healthcare costs and improve health outcomes in this population.
Article Synopsis
- Workplace violence is a significant issue, particularly in healthcare, with emergency department workers facing heightened risks of mental and physical health problems.
- The study aimed to investigate the frequency of violence from patients and coworkers experienced by emergency department professionals and analyze its impact on factors like burnout and job satisfaction.
- Findings revealed high levels of both physical and non-physical violence, with variations among roles; administrative staff faced more non-physical violence, while nurses showed higher job satisfaction and engagement levels.
A potential protective role of cognitive reserve proxies against frailty has been suggested in older adults. We explored the cross-sectional association between cognitive reserve indicators and frailty phenotype. Data were obtained from the UK Biobank.
View Article and Find Full Text PDFImmunotherapy has improved survival rates in patients with cancer, but identifying those who will respond to treatment remains a challenge. Advances in proteomic technologies have enabled the identification and quantification of nearly all expressed proteins in a single experiment. Integrating mass spectrometry with high-throughput technologies has facilitated comprehensive analysis of the plasma proteome in cancer, facilitating early diagnosis and personalized treatment.
View Article and Find Full Text PDFObjective: Here we estimate the cost-effectiveness of olaparib in the Spanish National Health Service (SNHS) as adjuvant treatment of early germline mutations in the BRCA1/2 genes (gBRCAm) HER2-negative (HER2neg) breast cancer (BC) with high risk of recurrence.
Methods: A semi-Markov model was adapted to the Spanish healthcare setting, using the perspective of the SNHS, and a lifetime horizon. Two scenarios were compared: receiving olaparib versus standard of care (SoC) treatment.