Long gap esophageal atresia repair using the foker tecnique: a 19 years experience.

Esophageal atresia (EA) with a 3-cm gap or longer and a very short distal segment represents the extreme of this disorder's spectrum, the treatment of which can be challenging. Management of newborns with long-gap esophageal atresia (LGEA) remains a challenge for pediatric surgeons. The inclusion criteria in the study were as follows: long gap esophageal atresia, Foker technique, at least 10 years follow up.

Molecular characterisation and antibiotic susceptibility of meningococcal isolates from healthy men who have sex with men.

Objectives: To evaluate and characterise meningococcal carriage among healthy men who have sex with men (MSM) within a screening programme for infection at the San Gallicano Dermatological Institute, Italy.

Methods: A total of 441 MSM attending the STI/HIV Centre of the San Gallicano Institute, Rome, Italy, in 2016 were routinely screened for infection by pharyngeal and rectal swabs. isolates were evaluated for antibiotic susceptibility and characterised by whole genome sequencing.

Gastrointestinal function after surgical correction of Hirschsprung's disease: long-term follow-up in 81 patients.

Background: Despite significant developments in understanding the pathological anatomy and physiology of Hirschsprung's disease (HD), the follow-up of children with HD remains far from clear. Treatment results for HD are not uniformly successful and the interpretation of the result by the parents and child may differ from that of the surgeon. Our goal is to analyze quality of life and differences in functional outcomes in children operated on using the pediatric incontinence / constipation scoring system (PICSS) validated in a regulatory group.

Limitations and obstacles of the spontaneous adverse drugs reactions reporting: Two "challenging" case reports.

Introduction: Nowadays, based on several epidemiological data, iatrogenic disease is an emerging public health problem, especially in industrialized countries. Adverse drugs reactions (ADRs) are extremely common and, therefore, clinically, socially, and economically worthy of attention. Spontaneous reporting system for suspected ADRs represents the cornerstone of the pharmacovigilance, because it allows rapid detection of potential alarm signals related to drugs use.