Multiple adverse childhood experiences and asthma onset in adulthood: Role of adulthood risk factors as mediators.

Objective: This population-based study of 21,902 Finnish adults examined whether adulthood risk factors for asthma mediate the association between the exposure to multiple adverse childhood experiences (ACEs) assessed retrospectively and the risk of new-onset asthma in adulthood.

Methods: Baseline characteristics, occurrence of ACEs, and risk factors of asthma in adulthood were collected with a postal survey at baseline in 1998. The participants were linked to records on incident asthma from national health registers from 1999 to 2012.

Change in β-agonist use after severe life events in adults with asthma: A population-based cohort study: Life events and bronchodilator usage among adults with asthma.

Objective: This prospective, population-based cohort study of 1102 Finnish adults with asthma, examined whether exposure to stressful life events is associated with the intensity of usage of inhaled short-acting β-agonists.

Methods: Survey data was collected by two postal questionnaires. Baseline characteristics were obtained in 1998 and data on 19 specific stressful events (e.

Childhood adversities and adult-onset asthma: a cohort study.

Objectives: Childhood adversities may be important determinants of later illnesses and poor health behaviour. However, large-scale prospective studies on the associations between childhood adversities and the onset of asthma in adulthood are lacking.

Design: Prospective cohort study with 7-year follow-up.

Stressful life events and the onset of asthma.

The status of stressful life events as a risk factor for asthma is unclear and may be dependent on pre-existing allergic rhinitis. This study examined whether exposure to stressful life events predicted the onset of asthma in adults. This is a prospective, population-based cohort study of 16,881 males and females, aged 20-54 yrs and free of diagnosed asthma at the beginning of the follow-up (January 1, 2004).

Resting- and postexercise-ECG findings in an adult Lapp population.

Resting electrocardiograms were recorded in 412 and postexercise-ECGs in 186 Lapp men and women over the age of 40. Abnormalities in the resting-ECG suggestive of old myocardial infarction by the Minnesota code were found in 7% of the men and in 1% of the women. ST-depression compatible with myocardial ischaemia in the resting-ECG were found in 3% of men aged 40-49 years and in 5% of women of the same age; and increased with age up to 11% and 24% in men and women, respectively, over the age of 60.