Publications by authors named "R Leelawattana"
Background: Diabetes mellitus is a significant global health issue, and alternative treatments from natural products like L. [Clusiaceae] or GM are being explored for their potential benefits. This study focused on evaluating the hypoglycemic effects of GM on diabetic rodent models.
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- Cushing's disease leads to higher health risks, and osilodrostat, an oral medication, has shown effectiveness in reducing cortisol levels in patients during two key studies.
- This analysis included 210 patients, with 27% being of Asian origin; results indicate that both Asian and non-Asian patients showed similar improvements in health measures, although Asian patients required lower doses of osilodrostat.
- Adverse events (AEs) were common, with Asian patients experiencing more issues related to low cortisol levels and pituitary tumor enlargement compared to their non-Asian counterparts, suggesting greater sensitivity to the treatment in Asian individuals.
Purpose: This study aims to assess the association between admission-corrected serum calcium phosphate (CaPO) levels and the risks of in-hospital acute kidney injury (AKI) and mortality, hypothesizing a dose-dependent relationship between serum CaPO concentrations and the likelihood of developing AKI.
Methods: This large retrospective cohort study analyzed hospitalized adult patients who had serum calcium, phosphate, and albumin levels measured within 24 hours of admission between January 2014 and December 2018. Piecewise regression was employed to identify the optimal CaPO cutoff values for predicting in-hospital AKI and mortality.
Objectives: To identify the factors associated with venous collaterals in Thai patients with cerebral venous thrombosis.
Materials And Methods: This retrospective 20-year cohort study enrolled patients diagnosed with cerebral venous thrombosis between January 2002 and December 2022. Data was collected from the electronic medical record, and venous collaterals were independently reviewed by two neuroradiologists using the Qureshi classification.
Objectives: Studies focusing on intracranial hemorrhage (ICH) in patients with cerebral venous thrombosis (CVT) are limited; thus, we aimed to identify factors associated with the occurrence of ICH in Thai patients with CVT.
Methods: This retrospective cohort study recruited patients with CVT admitted to a tertiary university-based hospital between 2002 and 2022. The baseline characteristics, clinical presentations, radiographic findings, and etiologies were compared between the ICH and non-ICH groups.