Guideline choice for CTG analysis influences first caesarean decision.

Objective: To compare intrapartum cardiotocography (CTG) analysis in case of first caesarean section (CS) for non-reassuring CTG according to international guidelines.

Methods: Four ObGyns retrospectively analysed first CS for non-reassuring CTG during labour blind to neonatal outcome. CTG were analysed according to French National College of Obstetricians and Gynaecologists (CNGOF) and to the FIGO guidelines.

[Can we foretell preeclampsia?].

Predicting PE would enable a better understanding of the physiological mechanisms responsible for this disease. It would also permit the identification of an at-risk population and consequently ease the set up of clinical trials. Over 12,000 articles have been published on this subject.

Preeclampsia: impaired inflammatory response mediated by Toll-like receptors.

Monocytes may be activated in preeclampsia (PE). Toll-like receptor (TLR)-4 and TLR-2 are involved in inflammatory responses of monocytes. The objective of this study was to evaluate the production of tumor necrosis factor (TNF), an inflammatory cytokine, and interleukin (IL)-10, an immunoregulatory cytokine, by monocytes from PE patients stimulated with TLR ligands.

Development and internal validation of a nomogram to predict macrosomia.

Objective: To develop a nomogram to predict macrosomia with a combination of clinical and ultrasound variables.

Methods: Data from 194 women who underwent sonographic fetal weight estimation were used to develop and calibrate a nomogram to predict fetal macrosomia. The nomogram was subjected to 200 bootstrap resamples for internal validation and to reduce overfit bias.

[Delivery of a macrosomic infant: factors predictive of failed labor].

Objective: To determine risk factors of failed labor in case of fetal macrosomia.

Materials And Methods: Medical charts of two hundred and forty six women who delivered macrosomic infants (>4,000g) between January 2004 and May 2005 were reviewed. Maternal and obstetrical data were analyzed by mode of delivery.