Publications by authors named "R Leao"
Article Synopsis
- Adult neurogenesis is the process of generating new neurons in the mammalian brain throughout life, which is linked to the HPA axis and mood disorders.
- Psychedelic compounds, including phenethylamines and tryptamines, are being explored as potential therapies for neuropsychiatric disorders, with many studies indicating their role in promoting adult neurogenesis.
- This systematic review analyzes existing research on the effects of various psychedelics on neurogenesis and brain plasticity, aiming to inform future therapeutic strategies for mental health issues.
Pseudomonas aeruginosa, an opportunistic pathogen often found in Healthcare-associated infections (HAI), has shown increased resistance to carbapenems (imipenem, meropenem, doripenem), the primary treatment options. We've seen a rise in carbapenemase-producing P. aeruginosa in Brazil, including NDM-producers.
View Article and Find Full Text PDFBackground: Intraductal carcinoma (IDC) and cribriform pattern (Crib) of prostate cancer are recognised as independent prognosticators of poor outcome, both in prostate biopsies and radical prostatectomy (RP) specimens.
Objective: This study aimed to determine the predictive value of Free-to-total PSA ratio (FPSAR) in identifying missed IDC/Crib at the time of biopsy as compared to the final surgical specimen.
Materials And Methods: Patients who underwent RP between January 2015 and December 2022 were included in the study.
Article Synopsis
- - Atypical hemolytic uremic syndrome (aHUS) is a complex disorder caused by issues with the complement system, often leading to serious blood and kidney problems.
- - A case study of a 38-year-old woman shows that aHUS can develop after gastroenteritis even without the common genetic markers or abnormal complement levels.
- - This situation underlines the difficulties in diagnosing and managing aHUS when typical signs are missing, pointing to the need for personalized treatment strategies.
Cartwheel (CW) neurons are glycinergic interneurons in the dorsal cochlear nucleus (DCN) that exhibit spontaneous firing, resulting in potent tonic inhibition of fusiform neurons. CW neurons expressing open ATP-sensitive potassium (K) channels do not fire spontaneously, and activation of K channels halts spontaneous firing in these neurons. However, the conditions that regulate K channel opening in CW neurons remain unknown.
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