Publications by authors named "R Leaback"
Article Synopsis
- Postoperative atrial fibrillation (POAF) is common after cardiac surgery and has well-documented short-term negative impacts, but its long-term effects on patient health are less understood.
- A study of over 30,000 patients aged 55-90 who underwent open-heart surgery from 2010 to 2019 found that those with POAF had significantly higher risks of complications like recurrent atrial fibrillation, heart failure, chronic kidney disease, and increased mortality rates.
- The findings emphasize the importance of monitoring and managing POAF in postoperative patients, as it relates to poorer long-term health outcomes.
Background: Postoperative atrial fibrillation (POAF) is associated with increased morbidity and mortality. Epicardial injection of botulinum toxin may suppress POAF.
Objectives: This study sought to assess the safety and efficacy of AGN-151607 for the prevention of POAF after cardiac surgery.
Purpose:: Dexamethasone intravitreal implant and intravitreal ranibizumab are indicated for the treatment of macular edema secondary to retinal vein occlusion. This non-inferiority study compared dexamethasone with ranibizumab in patients with branch retinal vein occlusion.
Methods:: In this randomized, 12-month head-to-head comparison, subjects with branch retinal vein occlusion were assigned to dexamethasone 0.
PurposeTo assess the safety and efficacy of an eye drop combining osmoprotectants, carboxymethylcellulose and hyaluronic acid (O/CMC/HA) in reducing symptomatic, moderate to severe dry eye, compared with HA.MethodsIn this investigator-masked, randomised study, patients instilled 1-2 drops/eye of O/CMC/HA or HA (2-6 times/day) for 3 months. Primary endpoint: mean change in Global Ocular Staining Score (GOSS) from baseline at day 35.
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