The Influence of Progressive Static Load on the Ability of Dental Implants to Withstand Overloading Forces: An Experimental Study in Dogs.

Purpose: To examine the effect of controlled progressive orthodontic loading on bone around implants subjected to overloading forces.

Materials And Methods: Bilateral edentulous alveolar ridges were created in the posterior maxilla of five beagle dogs and left to heal for an 8-week period, after which 40 implants were placed. In the overloading group (OL), 16 implants were inserted and left to osseointegrate for 16 weeks; impressions were made, and metal crowns were mounted on with supraocclusal contacts with the antagonist teeth.

The Ability of Quantitative, Specific, and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases.

The analysis of the disease-specific oral and systemic biomarkers in saliva and oral fluids (i.e., mouth rinse, gingival crevicular fluid (GCF), and peri-implantitis fluid (PISF)) is demanding.

Slow conduction through an arc of block: A basis for arrhythmia formation postmyocardial infarction.

Introduction: The electrophysiologic basis for characteristic rate-dependent, constant-late-coupled (390 + 54 milliseconds) premature ventricular beats (PVBs) present 4-5 days following coronary artery occlusion were examined in 108 anesthetized dogs.

Methods And Results: Fractionated/double potentials were observed in injured zone bipolar and composite electrograms at prolonged sinus cycle lengths (1,296 ± 396 milliseconds). At shorter cycle lengths, conduction of the delayed potential decremented, separating from the initial electrogram by a progressively prolonged isoelectric interval.

Intermittent vs. Continuous Anticoagulation theRapy in patiEnts with Atrial Fibrillation (iCARE-AF): a randomized pilot study.

Purpose: We hypothesized that intermittent anticoagulation based on daily rhythm monitoring using the novel oral anticoagulants (NOACs) is feasible and safe among patients with paroxysmal atrial fibrillation (AF).

Methods: Patients with paroxysmal AF and ≥1 risk factors for stroke were randomized to either intermittent or continuous anticoagulation. Those in the intermittent group were instructed to transmit a daily ECG using an iPhone-based rhythm monitoring device.

Functional aspects of His bundle physiology and pathophysiology: Clinical implications.

In this review we present evidence from many experimental studies which challenge the concept of predestination of His bundle fibers. Using both intra- and extracellular His bundle pacing in the context of atrio-ventricular block and the development of bundle branch blocks these experimental studies provide the underlying mechanisms for the recent clinical findings showing the benefits of permanent His bundle pacing.