Publications by authors named "R Latino"
Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and emotional burden for the patients and caregivers. It is characterised by a (at least initially) selective degeneration of the frontal and/or temporal lobe, generally leading to behavioural alterations, speech disorders, and psychiatric symptoms. Despite the recent advances, given its extreme heterogeneity, an overview that can bring together all the data currently available is still lacking.
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- ApoE is a special protein in our body that helps transport cholesterol and fat, and it comes in different types, which can affect the risk of getting Alzheimer's disease.
- Scientists are trying to understand how these different ApoE types impact the brain and cause issues like inflammation and memory problems.
- There are new treatments being tested that focus on changing or mimicking ApoE to help people who might get Alzheimer's, especially those with the version that increases their risk.