Training Characteristics Related to (the Changes in) Durability in Semiprofessional Cyclists.

Purpose: To provide insights into a dose-response relationship between training and time-trial performance, as assessed in both a "fresh" and a "fatigued" state (durability), including proposed underlying factors for durability: gross efficiency and substrate oxidation (FatOx and CarbOx).

Methods: Ten male semiprofessional cyclists underwent a performance test in both "fresh" and "fatigued" state (after 38.6 [4.

Preparation of Human Atrial Trabeculae for Ex Vivo Analysis of Human Myocardial Function.

Human myocardial function can be investigated in the laboratory using human atrial trabeculae. These multicellular preparations provide a translatable model for assessing the ex vivo contractility, electrophysiology, and ionic and metabolic underpinnings of human cardiac muscle. Here, we detail the materials and methods required to determine the baseline function of a human atrial trabecula, from dissection to stimulation.

Pacing analysis and comparison of TOP-10 and NOT TOP-10 Ultra Trail Cape Town 100-km finishers.

Background: Pacing strategies during endurance efforts vary depending on athlete experience, race length, and terrain. In ultramarathon trail running the specific race route profile can have a significant impact on optimal pacing strategy. The aim of this study was to determine the relationship between uphill, downhill and level running with overall performance and to compare the difference in pacing strategies between top 10 (TOP-10) and non-top 10 (NOT TOP-10) finishers of a 100-km ultra-trail marathon with +5000-m elevation gain.

Physical Health and Socioeconomic Status in Ambulatory Adults With Bilateral Spastic Cerebral Palsy.

Socioeconomic status (SES) tends to influence an individual's access to health care. It is commonly assumed that a poorer SES is associated with a weaker physical health status, especially in disadvantaged populations such as people with cerebral palsy (CP). However, to our knowledge, no study has looked at this assumption.