[Primary lateral sclerosis and lung adenocarcinoma].

Introduction: Lung cancer is frequently associated with paraneoplastic syndromes, sometimes uncommon, among which motor neurone disease is sometimes described, including primary lateral sclerosis, a disorder characterized by slowly progressive cortico-spinal dysfunction due to the degeneration of the upper motor neurone.

Case Report: We report a case of primary lateral sclerosis developing in a young woman 9 months after the diagnosis of metastatic adenocarcinoma of the lung. Our patient showed a spastic quadriparesis, dysarthria and bulbar symptoms without amyotrophy nor fasciculation.

Bronchial necrosis and granuloma induced by the aspiration of a tablet of ferrous sulphate.

Aspiration of foreign bodies occurs mainly in children and elderly people. When the foreign body is a tablet, this event can be more severe due to the local release of active molecules. We observed spontaneously regressing bronchial necrosis and granuloma due to the aspiration of a tablet of ferrous sulphate.

[Nontumoral nervous complications of bronchial cancer].

The authors present 52 cases of neurological complications of bronchial cancer including 35 cases of non-tumoral manifestations. They stress the frequency and the severity of these complications which are dominated by cerebral vascular accidents and describe the pathogenic features of this particular complication. They define the complications accessible to treatment: iatrogenic pathology, deficiency disorders and certain paraneoplasic syndromes.

[Triple biphasic chemotherapy in the treatment of small-cell bronchial cancer].

Forty-three patients with small-cell bronchial carcinoma were treated with sequential combination chemotherapy of the CMC-VAP type alternating every 6 weeks. Toxicity affected mostly blood cells and occurred during induction. The response rate was 60% in circumscribed forms with a median survival of 15 months, and 30% in diffuse forms with a median survival of 6 months.

[Alveolar cancer (author's transl)].

Alveolar cancer is the only true cancer of the lung as opposed to the common bronchial cancer. The authors defend this thesis by contesting the excessive usage of the expression bronchiolo-alveolar cancer and by supporting it with 12 original observations together with the literature review. The anatomo-pathological data are reported and discussed in order to analyze the reliability of the observations; diagnosis can vary according to the methods used in comparing the bronchial cytology and the examination of the operation tissue samples; the evolutive back search of observations revealed that out of 9 operated cases with localized involvement, 5 patients were still alive 2 years later.