Publications by authors named "R L Whelan"
This study investigated the effects and interactions among diets formulated to have high starch-to-lipid ratios (S:L), amino acid density [indicated as % digestible lysine (DigLys)], and AME on growth performance and carcass characteristics of heat stressed broilers. A {3,3} simplex lattice design was used to assess relative effects and generate predictive models. Three basal finisher diets were formulated to have the highest S:L ratio (Basal A; 20:1), DigLys (Basal B; 1.
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- The study utilized machine learning models to identify reliable diagnostic markers for eating disorders, major depressive disorder, and alcohol use disorder, targeting young adults aged 18-25.
- The classification models showed high accuracy rates (AUC-ROC ranging from 0.80 to 0.92) even without considering body mass index and highlighted shared predictors like neuroticism and hopelessness.
- Additionally, the models were moderately successful in predicting future symptoms related to eating disorders, depression, and alcohol use in a longitudinal sample of adolescents, indicating the potential for improved diagnosis and risk assessment in mental health.
Introduction: A growing literature has shown that exposure to adverse life events during childhood or adolescence is associated with the presence of psychotic-like experiences (PLEs), which is in turn associated with the risk of psychotic outcomes. Ruminative thinking, i.e.
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- This study uses multi-modal MRI to investigate neurobiological differences between anorexia nervosa (AN) and bulimia nervosa (BN), revealing structural and functional brain changes linked to these eating disorders.
- Key findings include reduced gray matter volume in specific brain regions (like the orbitofrontal cortex) and decreased cortical thickness, particularly in anorexia patients, which are associated with impulsivity and cognitive restraint regarding eating behaviors.
- The results suggest that these brain changes affect reward processing and contribute to the persistence of eating disorder symptoms, highlighting potential targets for future treatment interventions.