Publications by authors named "R L Sandler"
Background: Seismocardiographic signals (SCG) are chest wall vibrations induced by mechanical cardiac activities. This study investigated the morphological changes in the SCG signal due to respiration and exercise.
Methods: Fifteen healthy subjects were recruited, and SCG was acquired before and after exercise.
Article Synopsis
- Introducing new genes and species into ecosystems can provide benefits like preventing extinctions, but it also poses risks and raises ethical concerns.
- The conservation community has made attempts to create guidelines, yet there is a need for broader principles to help navigate these complex decisions.
- This text proposes an inclusive set of principles that consider biological, legal, social, cultural, and ethical factors to assist conservation managers in making informed choices about emerging technologies.
Seismocardiographic (SCG) signals are chest wall vibrations induced by cardiac activity and are potentially useful for cardiac monitoring and diagnosis. SCG waveform is observed to vary with respiration, but the mechanism of these changes is poorly understood as alterations in autonomic tone, lung volume, heart location and intrathoracic pressure are all varying during the respiratory cycle. Understanding SCG variability and its sources may help reduce variability and increase SCG clinical utility.
View Article and Find Full Text PDFBackground And Aims: There are few known risk factors for inflammatory bowel disease (IBD), an autoimmune disease characterized by chronic intestinal inflammation. Use of specific pesticides has been associated with higher incidence of IBD among pesticide applicators and their spouses, but no study has examined pesticide exposure in early life, a period where the human immune system undergoes rapid changes. We evaluated pesticide use during childhood and adolescence and incidence of IBD among US women enrolled in the Sister Study.
View Article and Find Full Text PDFBackground & Aims: Glucagon-like peptide-1-receptor agonists (GLP1-RAs) have been associated with greater retention of gastric contents, however, there is minimal controlled, population-based data evaluating the potential adverse effects of GLP1-RA in the periprocedural setting. We aimed to determine if there is increased risk of aspiration and aspiration-related complications after upper endoscopy in patients using GLP1-RAs.
Methods: We used a nationwide commercial administrative claims database to conduct a retrospective cohort study of patients aged 18 to 64 with type 2 diabetes who underwent outpatient upper endoscopy from 2005 to 2021.