Alzheimers Dement
December 2024
Background: Language impairment manifestations in patients with the semantic variant of primary progressive aphasia (S-PPA) include surface dysgraphia. Word and pseudoword dictation helps characterize errors in these patients' writing to better conduct their therapeutic strategies. Few studies have addressed written language in patients with dementia, and even fewer have done so in PPA.
View Article and Find Full Text PDFMultidrug resistance (MDR) is a major challenge in cancer research. Collateral sensitizers, compounds that exploit the enhanced defense mechanisms of MDR cells as weaknesses, are a proposed strategy to overcome MDR. Our previous work reported the synthesis of two novel Isoquinolinequinone (IQQ) N-oxides that induce collateral sensitivity in MDR ABCB1-overexpressing non-small cell lung cancer (NSCLC) and colorectal cancer cells.
View Article and Find Full Text PDFHealth Sci Rep
December 2024
Background And Aims: The current study aimed to compare the effects of 12 weeks of moderate versus high-intensity water aerobics on muscle strength, body composition, lipid profile, blood pressure, and quality of life in both adults and older adults.
Methods: Twenty-one women (65.19 ± 9.
Front Plant Sci
December 2024
Wheat is an essential staple food, and its production and grain quality are affected by extreme temperature events. These effects are even more relevant considering the increasing food demand for a growing world population and the predicted augmented frequency of heat waves. This study investigated the impact of simulated heat wave (HW) conditions imposed during grain filling on starch granule characteristics, endosperm ultrastructure, and transcriptomic modulation of genes involved in starch synthesis and degradation.
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