Severe Reversible Heart Failure Enhanced by Sorafenib Treatment for Hepatocellular Carcinoma.

The multitarget oral tyrosine kinase inhibitor sorafenib is an effective first-line treatment option in unresectable hepatocellular carcinoma. Through its mechanism of action, it has been associated with cardiotoxicity, mainly hypertension, which is usually low-grade and well-managed with behavioral changes and antihypertensor treatment adjustment, if needed. Acute, symptomatic heart failure is rarely described.

Investigating students' intention to utilize an e-learning platform in an aviation institution during the COVID-19 pandemic.

Aviation College is a higher education institution that shifted to e-Learning as the education platform during the COVID-19 Pandemic. This shift has posed challenges, especially in developing countries like the Philippines. This study aims to evaluate students' intentions toward using an e-learning platform at a collegiate aviation institution during the pandemic by employing an integrated extended Technology Acceptance Model (TAM) and Seddon's Information System (IS) Success Model.

Ptosis in human immunodeficiency virus-infected patients under long-term antiretroviral treatment.

Objective: To present cases of ptosis in HIV-1 patients on long-term antiretroviral therapy (ART) and review the existing literature.

Methods: Five HIV-1-positive patients with slowly progressive bilateral ptosis underwent a comprehensive diagnostic evaluation, including imaging studies, neurophysiological testing, muscle biopsy, and genetic analysis. A literature review was conducted.

Rare Becomes Rarer: Neuroendocrine Carcinoma of the Cervix With Synchronous Breast, Pancreatic, and Ovarian Metastases.

Neuroendocrine carcinoma of the cervix (NECC) is a rare and extremely aggressive disease. Treatment options are scarce (mainly consisting of platinum-based chemotherapy combinations), and randomized controlled trials are lacking, leading to a very poor prognosis. It is prone to early metastasis, often with more than one affected site at diagnosis.

Analysis of Transgender and Gender-Diverse Topics Within Diversity, Equity, and Inclusion Curricular Content in Pediatric Anesthesiology Fellowship Programs in the United States and Canada-A Prospective Survey.

Background: Transgender and gender-diverse individuals experience higher burdens of health disparities compared to their cisgender counterparts. Contributing factors include decreased access and denial of care, experiences and fear of medical violence, and increasing legislative barriers. These patients often report having to educate healthcare professionals due to lack of expertise of transgender and gender-diverse issues within the medical community, with training deficits observed at all levels of medical training.