Publications by authors named "R L Moy"

Background: For three decades, fractional ablative CO lasers have been used for skin rejuvenation. With breakthroughs in laser technology and expanding popularity, new recommendations and suggestions arise on a regular basis.

Objective: To develop up-to-date clinical recommendations on safety measures, therapeutic framework, and techniques to improve treatment outcomes.

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Article Synopsis
  • PMN-MDSCs are dysfunctional immune cells that hinder the effectiveness of cancer immunotherapy, particularly by affecting the immune response in gastric cancer.
  • The study developed a fusion protein, TFF2-MSA, that acts as a partial agonist for the CXCR4 receptor, enhancing the effects of anti-PD-1 therapy to reduce tumor growth and improve survival in various gastric cancer models.
  • TFF2-MSA specifically reduces harmful PMN-MDSCs while keeping helpful neutrophils intact, which boosts the CD8 T cell-mediated anti-tumor response, contrasting with traditional CXCR4 antagonism that did not show similar benefits.
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Diffuse-type gastric cancer (DGC) accounts for approximately one-third of gastric cancer diagnoses but is a more clinically aggressive disease with peritoneal metastases and inferior survival compared with intestinal-type gastric cancer (IGC). The understanding of the pathogenesis of DGC has been relatively limited until recently. Multiomic studies, particularly by The Cancer Genome Atlas, have better characterized gastric adenocarcinoma into molecular subtypes.

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While conventional in-office phototherapy has long been utilized as a successful treatment for atopic dermatitis (AD), it is associated with potential barriers including inconvenience, poor adherence, time and financial expense. In this retrospective study, we examine the efficacy, adherence, and patient-satisfaction of using adjunctive at-home, self-administered phototherapy utilizing a novel handheld narrow-band ultraviolet B (NB-UVB) device for the treatment of refractory mild to severe AD. Included AD patients were initially trained on proper use of the device.

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