Coastal ecosystems are degraded worldwide and oyster reefs are among the most threatened coastal habitats. Oysters are a critical ecosystem engineer and valuable fishery species, thus effective management strategies must balance tradeoffs between protecting reef ecosystems and continued human use. Management practices for oysters commonly incorporate shell replenishment (provisioning hard substrates to increase reef relief) and spatial management (rotational harvest areas or sanctuaries); however, the impact of these practices on reef dynamics and fisheries outcomes are poorly understood, particularly on harvested reefs.
View Article and Find Full Text PDFThis study assessed effectiveness of regulations reducing environmental butyltin concentrations in Southern Chesapeake Bay over the 1999-2021 period. Water column monitoring of the Elizabeth River from 1999 to 2006 demonstrated decreasing TBT from 2003 to 2006 (average >1 ng/L at most stations) to <1 ng L by 2019 but with higher concentrations of degradation products DBT and MBT. TBT degrades to DBT and MBT within sediments, and releases degradation products over time.
View Article and Find Full Text PDFWomen with extremely dense breasts are at a higher risk of breast cancer, and the sensitivity of mammography in this group is reduced due to the masking effect of overlapping tissue. This review examines supplemental screening methods to improve detection in this population, with a focus on MRI. Morphologic techniques offer limited benefits, digital breast tomosynthesis (DBT) shows inconsistent results, and ultrasound (US), while improving cancer detection rates (CDR), results in a higher rate of false positives.
View Article and Find Full Text PDFInterleukin (IL)-7 promotes T cell expansion during lymphopenia. We studied the metabolic basis in CD4 T cells, observing increased glucose usage for nucleotide synthesis and oxidation in the tricarboxylic acid (TCA) cycle. Unlike other TCA metabolites, glucose-derived citrate does not accumulate upon IL-7 exposure, indicating diversion into other processes.
View Article and Find Full Text PDF