subsp. RadD binds Siglec-7 and inhibits NK cell-mediated cancer cell killing.

is an oral commensal bacterium that can colonize extraoral tumor entities, such as colorectal cancer and breast cancer. Recent studies revealed its ability to modulate the immune response in the tumor microenvironment (TME), promoting cancer progression and metastasis. Importantly, subsp.

Antiarrhythmic Mechanisms of Epidural Blockade After Myocardial Infarction.

Background: Thoracic epidural anesthesia (TEA) has been shown to reduce the burden of ventricular tachycardia in small case series of patients with refractory ventricular tachyarrhythmias and cardiomyopathy. However, its electrophysiological and autonomic effects in diseased hearts remain unclear, and its use after myocardial infarction is limited by concerns for potential right ventricular dysfunction.

Methods: Myocardial infarction was created in Yorkshire pigs (N=22) by left anterior descending coronary artery occlusion.

Thoracic epidural blockade after myocardial infarction benefits from anti-arrhythmic pathways mediated in part by parasympathetic modulation.

Background: Thoracic epidural anesthesia (TEA) has been shown to reduce the burden of ventricular tachyarrhythmias (VT) in small case-series of patients with refractory VT and cardiomyopathy. However, its electrophysiological and autonomic effects in diseased hearts remain unclear and its use after myocardial infarction (MI) is limited by concerns for potential RV dysfunction.

Methods: MI was created in Yorkshire pigs ( =22) by LAD occlusion.

Antagonistic interaction between two key endodontic pathogens and .

Background: Endodontic infections are known to be caused by pathogenic bacteria. Numerous previous studies found that both and are associated with endodontic infections, with more abundant in primary infection while more abundant in secondary infection. Little is known about the potential interactions between different endodontic pathogens.

The derivative of tissue activation as a marker of arrhythmogenic myocardium.

Background: Mapping techniques to identify diseased myocardial substrate during ventricular tachycardia ablation procedures remain limited.

Objective: We hypothesized that tissue derivative of the voltage with respect to time (dV/dt), the slope of the unipolar ventricular electrogram registered by local ventricular activation, represents a unique parameter for identifying potential arrhythmogenic tissue in the ischemic scar border zone.

Methods: Using high-resolution electrical mapping, we examined dV/dt characteristics in the border zone of animals after chronic myocardial infarction (MI).