Modeling implications of the relationship between active and passive skeletal muscle mechanical properties.

It is challenging to obtain in vivo or in situ experimental data from human muscles due to the invasive nature of such measurements. As a result, many investigations of human performance, surgery, or skeletal adaptation are necessarily based on musculoskeletal models. The utility of such models will depend on the question being asked and the extent to which the model is sufficiently accurate to address that question.

Automate, Illuminate, Predict: A Universal Framework for Integrating Wearable Sensors in Healthcare.

Background: Wearable sensors have been heralded as revolutionary tools for healthcare. However, while data are easily acquired from sensors, users still grapple with questions about how sensors can meaningfully inform everyday clinical practice and research.

Summary: We propose a simple, comprehensive framework for utilizing sensor data in healthcare.

Specific tension of human muscle in vivo: a systematic review.

The intrinsic force production capability of human muscle can be expressed as "Specific Tension," or, the maximum force generated per cross-sectional area of muscle fibers. This value can be used to determine, for example, whether muscle quality changes during exercise, atrophy, disease, or hypertrophy. A value of 22.

Immunomodulatory Role of the Stem Cell Circadian Clock in Muscle Repair.

The circadian clock orchestrates vital physiological processes such as metabolism, immune function, and tissue regeneration, aligning them with the optimal time of day. This study identifies an intricate interplay between the circadian clock within muscle stem cells (SCs) and their capacity to modulate the immune microenvironment during muscle regeneration. We uncover that the SC clock provokes time of day-dependent induction of inflammatory response genes following injury, particularly those related to neutrophil activity and chemotaxis.