Paired associative stimulation improves motor function in the upper extremity in chronic incomplete spinal cord injury: a corroborative study.

Objective: To corroborate findings suggesting that spinally targeted paired associative stimulation improves upper extremity motor function in chronic incomplete spinal cord injury.

Design: Prospective interventional study.

Subjects: Five adults with chronic tetraplegia.

Critical exponents of correlated percolation of sites not visited by a random walk.

We consider a d-dimensional correlated percolation problem of sites not visited by a random walk on a hypercubic lattice L^{d} for d=3, 4, and 5. The length of the random walk is N=uL^{d}. Close to the critical value u=u_{c}, many geometrical properties of the problem can be described as powers (critical exponents) of u_{c}-u, such as β, which controls the strength of the spanning cluster, and γ, which characterizes the behavior of the mean finite cluster size S.

A reference framework for standardization and harmonization of CT radiomics features on cadaveric sample.

Radiomics features (RFs) serve as quantitative metrics to characterize shape, density/intensity, and texture patterns in radiological images. Despite their promise, RFs exhibit reproducibility challenges across acquisition settings, thus limiting implementation into clinical practice. In this investigation, we evaluate the effects of different CT scanners and CT acquisition protocols (KV, mA, field-of-view, and reconstruction kernel settings) on RFs extracted from lumbar vertebrae of a cadaveric trunk.

Insulin-Activated Signaling Pathway and GLUT4 Membrane Translocation in hiPSC-Derived Cardiomyocytes.

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a cell model now widely used to investigate pathophysiological features of cardiac tissue. Given the invaluable contribution hiPSC-CM could make for studies on cardio-metabolic disorders by defining a postnatal metabolic phenotype, our work herein focused on monitoring the insulin response in CM derived from the hiPSC line UKBi015-B. Western blot analysis on total cell lysates obtained from hiPSC-CM showed increased phosphorylation of both AKT and AS160 following insulin treatment, but failed to highlight any changes in the expression dynamics of the glucose transporter GLUT4.