Publications by authors named "R L LEIGHTON"
Aim: To determine the regional and ethnic differences in ocular axial elongation and refractive error progression in myopic and non-myopic children.
Methods: A retrospective analysis of 15 longitudinal clinical and population-based studies was conducted in the UK, Sweden, Australia (classified as European), China, and Vietnam (classified as East Asian) between 2005 and 2021. A total of 14,593 data points from 6208 participants aged 6-16 years with spherical equivalent from +6 to -6 D were analysed.
The escalating rise in antimicrobial resistance (AMR) coupled with a declining arsenal of new antibiotics is imposing serious threats to global public health. A pervasive aspect of many acquired AMR infections is that the pathogenic microorganisms exist as biofilms, which are equipped with superior survival strategies. In addition, persistent and recalcitrant infections are seeded with bacterial persister cells at infection sites.
View Article and Find Full Text PDFAims: Isolated fractures of the ulnar diaphysis are uncommon, occurring at a rate of 0.02 to 0.04 per 1,000 cases.
View Article and Find Full Text PDFHip Fracture Repair by the Post-Call Surgeon: A Multicenter Retrospective Review.
J Am Acad Orthop Surg Glob Res Rev
February 2024
Introduction: The purpose of this study was to evaluate surgeons' ability to perform or supervise a standard operation with agreed-upon radiologic parameters after being on call.
Methods: We reviewed a consecutive series of patients with intertrochanteric hip fractures treated with a fixed angle device at 9 centers and compared corrected tip-apex distance and reduction quality for post-call surgeons versus those who were not. Subgroup analyses included surgeons who operated the night before versus not and attending-only versus resident involved cases.
Article Synopsis
- The study explores the use of machine-learning prediction models in orthopaedic trauma, aiming to provide an overview, review reporting practices using the TRIPOD statement, and assess bias with the PROBAST tool.
- Out of 3,252 studies screened, 45 ML models were identified, with most focusing on hip fractures, and common outcomes being mortality and length of hospital stay.
- Findings reveal that while many models exist, they often have poor transparency in reporting (62% completeness) and a high risk of bias, primarily due to small sample sizes and inadequate analysis methods.