Publications by authors named "R L Binder"

Immune responses to tumors, comprising adaptive T cells and innate NK cells, arise very early in tumorigeneses and prior to detection of palpable tumors or before tissue pathology is evident. Yet, how nascent tumors evoke dendritic cell maturation and the resulting cytokine responses that are necessary for these effector anti-tumor immune responses is unknown. We have previously shown that CD91 expression on dendritic cells is important for immune surveillance, specifically for generating T cell and NK cell responses to nascent tumors.

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Article Synopsis
  • The interventional cardiology curriculum is a structured training program focused on advanced interventional procedures.
  • It outlines the necessary requirements for candidates, trainers, and training centers, including learning objectives and required skills.
  • Based on the European Core Curriculum, the program is adapted to meet Austria's healthcare needs and aims to deliver high-quality patient care.
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: There are limited data about left atrial appendage closure (LAAC) in patients with cancer. We therefore sought to compare the outcome after LAAC in patients with vs. without cancer in a multicentre registry.

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  • * This study analyzed data from over 900 high-risk AF patients to compare outcomes between those receiving LAAO and those getting traditional treatment (mostly oral anticoagulants).
  • * Results showed no significant differences in stroke or cardiovascular death rates, but LAAO patients experienced significantly less clinically relevant bleeding compared to those on conventional treatments.
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Renal sympathetic denervation (RDN) is an interventional supplement to medical treatment in patients with arterial hypertension. While the first sham-controlled trial, SYMPLICITY HTN‑3 was neutral, with improved procedural details, patient selection and follow-up, recent randomized sham-controlled trials of second-generation devices show a consistent blood pressure lowering effect of RDN, as compared to sham controls. These new data and the recent U.

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