Publications by authors named "R L Bezbaruah"

Squamous cell carcinoma is the most common malignancy of the head and neck. Pseudovascular squamous cell carcinoma (PSCC) is a rare variant that occurs commonly in the skin of the head and neck. However, oral cavity involvement is extremely rare, with only a few cases reported to date.

View Article and Find Full Text PDF
Article Synopsis
  • Extracellular vesicles (EVs), like exosomes, are crucial for cell communication and are being explored for targeted drug delivery due to their nanoscale size and biocompatibility.
  • Exosomes have advantages over traditional drug delivery methods, such as being less likely to trigger an immune response, but they face challenges like inconsistent production and low drug loading capacity.
  • Recent advancements in analysis tools may enhance the understanding of exosomes and improve their application in drug delivery, particularly in treating infections, as discussed in a review of studies from 2002 to 2023.
View Article and Find Full Text PDF
Article Synopsis
  • Plant-derived exosomes (PDEs) are tiny vesicles from plants that play crucial roles in biological functions such as gene regulation and cell communication, and show potential in improving health through diet.* -
  • This review analyzed various clinical and research studies to assess the effectiveness of PDEs as a form of precision therapy in treating different disorders, using methods like randomized clinical trials.* -
  • PDEs, which contain important molecules like lipids and microRNAs, exhibit promising applications in biomedicine, notably in enhancing drug delivery and therapeutic outcomes for conditions like inflammation and cancer.*
View Article and Find Full Text PDF

Background: Propolis is a resinous compound that is obtained from honey bees. It consists of numerous chemical constituents that impart different therapeutic action. The heart is the core of the body and cardiovascular disease (CVD) is a burden for the human being.

View Article and Find Full Text PDF

Nanoemulsions consist of a combination of several components such as oil, water, emulsifiers, surfactants and cosurfactants. Various techniques for producing nanoemulsions include high-energy and low-energy approaches such as high-pressure homogenization, microfluidization, jet disperser and phase inversion methods. The properties of a formulation can be influenced by elements such as the composition, concentration, size and charge of droplets, which in turn can affect the technique of manufacture.

View Article and Find Full Text PDF