Publications by authors named "R L Bergen"

Computed tomography (CT) scanners are essential for modern imaging but require around 600 projections from various angles. We present x-ray-induced acoustic computed tomography (XACT), a method that uses radiation-induced acoustic waves for three-dimensional (3D) x-ray imaging. These spherical acoustic waves travel through tissue at 1.

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Article Synopsis
  • Radiation-induced acoustics (RIA) could enhance imaging and dosimetry in radiology, but high noise levels necessitate averaging, leading to more radiation exposure for patients.
  • This paper introduces a discrete wavelet transform (DWT) filtering method to effectively denoise RIA signals, reducing the amount of averaging needed significantly—1000 times less for low-energy X-rays and 32 times less for high-energy X-rays.
  • The DWT approach showed robust performance across various radiation sources and matched low-pass filter results, paving the way for better clinical application of radiation-based acoustic imaging.
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Primary COVID-19 vaccination for children, 5-17 years of age, was offered in the Netherlands at a time when a substantial part of this population had already experienced a SARS-CoV-2 infection. While vaccination has been shown effective, underlying immune responses have not been extensively studied. We studied immune responsiveness to one and/or two doses of primary BNT162b2 mRNA vaccination and compared the humoral and cellular immune response in children with and without a preceding infection.

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Background And Objective: Training computer-vision related algorithms on medical images for disease diagnosis or image segmentation is difficult in large part due to privacy concerns. For this reason, generative image models are highly sought after to facilitate data sharing. However, 3-D generative models are understudied, and investigation of their privacy leakage is needed.

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Introduction: Patellofemoral pain (PFP) is a common musculoskeletal condition. Lower limb range of motion (LLROM) evaluates soft tissue flexibility over multiple joints as part of the kinetic chain. The aims were to study: 1) the reliability of a new LLROM test; 2) differences in LLROM between PFP patients and controls; and 3) the relationship between LLROM and pain-free knee function.

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