Publications by authors named "R L Barkin"

Article Synopsis
  • * The 2016 CDC guidelines for opioid prescribing have had adverse effects, leading to increased hospitalizations and mental health issues due to improper prescribing practices and rapid tapering of opioids.
  • * A panel of experts is creating new guidelines for prescribing opioids for chronic non-cancer pain, based on a thorough review of clinical and epidemiological evidence to improve patient outcomes.
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Major depressive disorder (MDD) is a chronic, debilitating mood disorder associated with poor medical outcomes. MDD has a multifactorial etiology with numerous biopsychosocial factors implicated as risk factors. Functional and psychiatric impairments have been evaluated in patients with liver cirrhosis; however, less is known about the prevalence and risk factors for the development of MDD in those patients.

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Mental health symptoms secondary to trauma exposure and substance use disorders (SUDs) co-occur frequently in both clinical and community samples. The possibility of a shared aetiology remains an important question in translational neuroscience. Advancements in genetics, basic science, and neuroimaging have led to an improved understanding of the neural basis of these disorders, their frequent comorbidity and high rates of relapse remain a clinical challenge.

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