Transparency-changing elastomers by controlling of the refractive index of liquid inclusions.

Complex materials that change their optical properties in response to changes in environmental conditions can find applications in displays, smart windows, and optical sensors. Here a class of biphasic composites with stimuli-adaptive optical transmittance is introduced. The biphasic composites comprise aqueous droplets (a mixture of water, glycerol, and surfactant) embedded in an elastomeric matrix.

Colloidal Engineering of Microplastic Capture with Biodegradable Soft Dendritic "Microcleaners".

The introduction of colloidal principles that enable efficient microplastic collection from aquatic environments is a goal of great environmental importance. Here, we present a novel method of microplastic (MP) collection using biodegradable hydrogel soft dendritic colloids (hSDCs). These dendritic colloids have abundant nanofibrils and a large surface area, which provide an abundance of interfacial interactions and excellent networking capabilities, allowing for the capture of plastic particles and other contaminants.

Effective growth hormone replacement with once-weekly somapacitan in Japanese children with growth hormone deficiency: Results from REAL4, a phase 3 clinical trial.

Objective: Somapacitan is a long-acting growth hormone (GH) derivative developed for the treatment of GH deficiency (GHD). This study evaluates the efficacy and tolerability of somapacitan in Japanese children with GHD after 104 weeks of treatment and after switch from daily GH.

Design: Subanalysis on Japanese patients from a randomised, open-labelled, controlled parallel-group phase 3 trial (REAL4, NCT03811535).

An overview of atmospheric aerosol and their effects on human health.

Epidemiologic investigations have previously been published in more than 200 papers, and several studies have examined the impacts of particle air pollution on health. The main conclusions now being made about the epidemiological evidence of particle pollution-induced health impacts are discussed in this article. Although there is no universal agreement, most reviewers conclude that particulate air pollution, particularly excellent combustion-cause contamination prevalent in many municipal and manufacturing environments, is a significant risk for cardiopulmonary sickness and mortality.

Effective GH Replacement With Somapacitan in Children With GHD: REAL4 2-year Results and After Switch From Daily GH.

Context: Somapacitan is a long-acting GH derivative for treatment of GH deficiency (GHD).

Objective: Evaluate the efficacy and tolerability of somapacitan in children with GHD after 2 years of treatment and after the switch from daily GH.

Design: A randomized, multinational, open-labelled, controlled parallel group phase 3 trial, comprising a 52-week main phase and 3-year safety extension (NCT03811535).