Publications by authors named "R Kuhlen"

Article Synopsis
  • The study examines the healthcare response to SARS-CoV-2 in Germany and Switzerland, highlighting disparities in treatment and surveillance that affected patient outcomes, particularly during ICU admissions and in-hospital mortality rates.
  • Using data from over 1.4 million cases across 386 German and 41 Swiss hospitals from 2019 to 2022, the research shows that German patients were older, had more comorbidities, and faced higher rates of ICU admission (28% vs. 20%) and in-hospital mortality (21% vs. 12%) compared to Switzerland.
  • The findings reveal significant healthcare discrepancies between the two countries, suggesting that varying treatment approaches and healthcare resources may have influenced the higher mortality
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Introduction: Type 2 diabetes mellitus (T2DM) is a leading cause of chronic kidney disease (CKD) globally. Both conditions substantially worsen patients' prognosis. Current data on German in-hospital CKD cohorts are scarce.

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Aims: Heart failure (HF) and chronic kidney disease (CKD) place significant challenges on the healthcare system, and their co-existence is associated with shared adverse outcomes. The multinational CaReMe project was initiated to provide contemporary, real-world epidemiological data on cardiovascular and reno-metabolic diseases. Utilizing data from the German CaReMe cohort, we characterize a multicentric HF population and describe in-hospital outcomes stratified for co-morbid CKD.

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Aims: Endemic SARS-CoV-2 infections still burden the healthcare system and represent a considerable threat to vulnerable patient cohorts, in particular immunocompromised (IC) patients. This study aimed to analyze the in-hospital outcome of IC patients with severe SARS-CoV-2 infection in Germany.

Methods: This retrospective, observational study, analyzed administrative data from inpatient cases ( = 146,324) in 84 German Helios hospitals between 1 January 2022 and 31 December 2022 with regard to in-hospital outcome and health care burden in IC patients during the first 12 months of Omicron dominance.

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The intensive care unit (ICU) is a scarce resource in all health care systems, necessitating a well-defined utilization. Therefore, benchmarks are essential; and yet, they are limited due to heterogenous definitions of what an ICU is. This study analyzed the case distribution, patient characteristics, and hospital course and outcomes of 6,204,093 patients in the German Helios Hospital Group according to 10 derived ICU definitions.

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