Practical implementation of automated insulin delivery systems in 2025: A French position statement update.

The advent of automated insulin delivery (AID) systems in 2020 marked a disruptive event in managing type 1 diabetes, benefiting children and adults alike. By 2024, advances in real-world data and research motivated an update to the French consensus on AID systems to expand accessibility, refine guidelines, and optimize patient follow-up. AID systems have consistently improved glycemic control by reducing HbA1c, increasing time-in-range (TIR), and minimizing hypoglycemia, with significant benefits even for specific populations such as individuals with poor glycemic control, brittle diabetes, children, very young children, pregnant women, those with insulin resistance or gastroparesis, or after bariatric surgery.

Time series analysis of Sentinel 1 A SAR data to retrieve annual rice area maps and long-term dynamics of start of season.

Rice is a vital staple crop globally, and accurate estimation of rice area was crucial for effective agricultural management and food security. Synthetic Aperture Radar (SAR) data has emerged as a valuable remote sensing tool for rice area estimation due to its ability to penetrate cloud cover and capture backscattered signals from rice fields. The backscatter signature of rice showed a minimum dB value at agronomic flooding indicating the Start of Season (SoS).

Identifying the Function of Kinesin Superfamily Proteins in Gastric Cancer: Implications for Signal Transduction, Clinical Significance, and Potential Therapeutic Approaches.

Gastric cancer (GC), a leading cause of cancer-related mortality, poses a significant global health challenge. Given its complex etiology, understanding the molecular pathways driving GC progression is crucial for developing innovative therapeutic strategies. Among the diverse proteins involved in cellular transport and mitotic regulation, kinesin superfamily proteins (KIFs) have emerged as key players in tumor biology.

Neoadjuvant Treatment in Rectal Cancer.

A major advance in rectal cancer was the evidence supporting short-course radiotherapy and long-course chemoradiotherapy. Both have been shown to improve local outcomes. Total neoadjuvant therapy (TNT) is the new kid on the block that provides further benefit of improving local responses as well as reducing systemic relapses, thus increasing overall survival.