Publications by authors named "R Kom-Tchameni"

Article Synopsis
  • Paraquat is a highly toxic herbicide linked to severe health risks and was banned in the EU in 2007.
  • A study analyzing 62 cases of paraquat poisoning in French Guiana from 2008 to 2015 found a poisoning incidence of 3.8 per 100,000 people, with most cases resulting from self-poisoning.
  • The study revealed that adults experienced higher mortality rates and ingested larger amounts compared to children, highlighting the critical importance of immediate medical intervention after exposure.
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Article Synopsis
  • The study focused on understanding the occurrence of infantile Pompe disease (IPD) in French Guiana, particularly within the African-American Maroon community.
  • Over a 13-year period, 19 newborns were identified with IPD, indicating an incidence rate of 1 in 4528 births, significantly higher in the Maroon population.
  • Genetic analysis showed that all affected infants had mutations linked to the disease, suggesting a double founder effect due to the community's limited genetic diversity.
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Article Synopsis
  • A significant Zika virus outbreak occurred in French Guiana and the West Indies from January to October 2016, with 1650 pregnant women affected.
  • ZIKV infection during pregnancy is linked to serious birth defects like microcephaly, but in this case, two children born from mothers with symptomatic infections showed no immediate abnormalities at birth.
  • Despite initial healthy appearances, both children later exhibited severe brain abnormalities related to in utero ZIKV exposure detected through MRI, suggesting potential implications of the mother's immune response or metabolic changes during infection.
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Multifocal tuberculosis in a child is rare event. Here we report a case of multifocal tuberculosis revealed by spinal tuberculosis in an eleven-year-old French Guianese girl. This observation underlines the difficulties, the consequences of delay, and the necessity of an early diagnosis of this disease for children.

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