Publications by authors named "R Klempfner"

Background: Age and sex can be estimated using artificial intelligence on the basis of various sources. The aims of this study were to test whether convolutional neural networks could be trained to estimate age and predict sex using standard transthoracic echocardiography and to evaluate the prognostic implications.

Methods: The algorithm was trained on 76,342 patients, validated in 22,825 patients, and tested in 20,960 patients.

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  • Cardiac rehabilitation programs often focus on aerobic fitness, neglecting muscle strength; this study aimed to assess the effects of a remote strength training program (RCR-ST) on cardiac rehab outcomes.
  • In a randomized study with 50 patients, one group used a targeted resistance training app while a control group received standard care, with assessments conducted at the start and after 16 weeks.
  • The RCR-ST group showed significant gains in muscle endurance and functional performance, along with heightened engagement and self-reported health improvements, highlighting the effectiveness of integrating strength training into cardiac rehabilitation.
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Background: We aimed to assess in a prospective multicenter study the quality of echocardiographic exams performed by inexperienced users guided by a new artificial intelligence software and evaluate their suitability for diagnostic interpretation of basic cardiac pathology and quantitative analysis of cardiac chamber and function.

Methods: The software (UltraSight, Ltd) was embedded into a handheld imaging device (Lumify; Philips). Six nurses and 3 medical residents, who underwent minimal training, scanned 240 patients (61±16 years; 63% with cardiac pathology) in 10 standard views.

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  • Current guidelines recommend implantable cardioverter-defibrillators (ICDs) for all patients with symptomatic heart failure and low left ventricular ejection fraction, but many may not benefit from them.
  • The study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to differentiate patients and gauge their likely survival benefits from ICDs.
  • Results indicated that among 2,177 patients, different MRSS risk groups had varying survival benefits from ICDs, suggesting that this score can help identify who might actually benefit from prophylactic ICD implantation.
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Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality. Acute exacerbations of COPD (AECOPD) drastically affect the clinical course of the disease. We aimed to evaluate the treatment of AECOPD in the internal medicine departments in Israel, nationwide.

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