Publications by authors named "R Kitazawa"
Bone is a unique organ crucial for locomotion, mineral metabolism, and hematopoiesis. It maintains homeostasis through a balance between bone formation by osteoblasts and bone resorption by osteoclasts, which is regulated by the basic multicellular unit (BMU). Abnormal bone metabolism arises from an imbalance in the BMU.
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- * Patient symptoms included fever, headache, and hearing loss, with tests revealing infection indicators and abnormal brain lesions confirmed through advanced imaging techniques.
- * Rapid pathological diagnosis, including immunohistochemistry and PCR, played a vital role in distinguishing the cryptococcoma from a potential malignant tumor, leading to successful antifungal treatment.
Article Synopsis
- - The study focuses on improving the diagnosis of primary central nervous system lymphoma (PCNSL) during surgery by using intraoperative rapid immunohistochemistry (IHC), along with cytology and flow cytometry (FCM) for quicker and more accurate treatment decisions.
- - In a trial involving 35 patients from April 2020 to January 2024, the addition of cytology and FCM to rapid IHC significantly sped up the time from surgery to chemotherapy initiation for PCNSL (1.6 days versus 7.3 days), demonstrating the benefits of this combined approach.
- - Final pathological diagnoses confirmed the consistency of intraoperative rapid IHC results, and the combined method resulted in changes in treatment strategy in certain
While the rapid decrease in estrogen is well known as the main cause of postmenopausal osteoporosis in women, the precise pathogenesis of senile osteoporosis in the elderly regardless of gender is largely unknown. The age-related epigenetic regulation of receptor activator NF-κB (RANK) gene expression was investigated with the use of a high-passaged mouse osteoclast progenitor cell line, RAW264.7, as an model of aging.
View Article and Find Full Text PDFBackground: Alveolar rhabdomyosarcoma (ARMS) shows a predilection for the peripheral extremities and is very rarely identified as a primary in the brain. Here, we report a case of ARMS with multiple lesions exclusively within the central nervous system (CNS).
Case Description: A 20-year-old man presented to our hospital with a gradually increasing headache and disturbance of consciousness.