Schistosoma mansoni: schistosomicidal effect of mefloquine and primaquine in vitro.

We investigated the effects of the anti-malarials mefloquine and primaquine against the juvenile and adult life stages of Schistosoma mansoniin vitro. Cercariae were incubated with 0.5 μg/ml, 1 μg/ml and 2 μg/ml mefloquine or primaquine and with 1 μg/ml praziquantel for 12h.

Schistosomula, pre-adults and adults of Schistosoma mansoni ingest fluorescence-labelled albumin in vitro and in vivo: implication for a drug-targeting model.

Summary Objective: Bilharziosis is one of the most important helminthal infections in humans and is caused by blood flukes of the genus Schistosoma. Three different life stages of the parasite occur within the mammalian host: schistosomula located in the skin, pre-adults located in the lung and adult worms located in the portal venous system. Erythrocytes are a major source of nutrient supply for adults.

[Global warming: trailblazer for tropical infections in Germany?].

Since 1850, the CO (2) content of the atmosphere has increased from 280 to 360 ppm, and the average surface temperature has risen from 14.6 to 15.3 C .

[Scorpions and scorpion stings in Jordan].

The scorpion fauna of Jordan consists of fourteen species belonging to three families (Buthidae, Scorpionidae and Diplocentridae), of which three species are poisonous: Leiurus quinquestriatus, Adroctonus crassicauda and Buthus occitanus. A key to all species is included. Five hundred and forty-seven cases of scorpion stings were reported during 1982-1985, including two fatalities.