Publications by authors named "R Kime"
Article Synopsis
- This study explored how oxygen levels change in skeletal muscles during body-weight exercises like Bulgarian split squats and push-ups, focusing on slow movements and sustained force.
- Thirteen untrained young males participated, and researchers used near-infrared spectroscopy to measure changes in oxygenated and deoxygenated hemoglobin in specific muscles during the exercises.
- Results indicated that oxygen dynamics varied significantly between different muscles, showing continuous deoxygenation in some areas during squats while revealing distinct patterns in push-ups, suggesting that individual variations in exercise skills could affect outcomes.
Article Synopsis
- Near-infrared spectroscopy (NIRS) has been used for over 30 years to assess skeletal muscle oxidative function during exercise, utilizing indicators like the deoxygenation rate and reoxygenation speed.
- These indicators correlate well with various muscle characteristics and have applications in studying chronic health issues, notably in patients with ischaemic heart failure.
- Despite advancements, challenges exist in using NIRS for measurement, particularly due to factors like subcutaneous adipose tissue thickness and variable mean pathlength during exercises, which can skew results and comparisons among different populations.
Brown adipose tissue (BAT) may be effective in preventing obesity and type II diabetes; however, there are no established reports on exercise-induced changes in BAT. This study focused on BAT variability in women undergoing resistance training (RT) interventions twice weekly for 10 weeks in cold environments. Fifteen participants were recruited: seven were randomly assigned to an RT group and eight to a control (CT) group.
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- The study explored how Nattokinase (NK) affects skin temperature after cold water immersion, focusing on blood flow's role in regulating skin temperature.
- Conducted with nine healthy men in a double-blinded, placebo-controlled design, the research tested NK against a placebo before the participants immersed their hands in cold water for one minute.
- Results showed that participants who took NK experienced a quicker recovery of skin temperature compared to the placebo group, suggesting NK might help prevent excessive blood vessel constriction, especially beneficial for individuals sensitive to cold.
Article Synopsis
- While treatments for human African trypanosomiasis (HAT) have advanced, new drugs are still needed as eradication becomes feasible.
- Researchers developed 2,4-diaminothiazoles that show strong effectiveness against the parasite causing HAT, using phenotypic screening to enhance their drug-like properties.
- Despite promising initial results, the compounds failed to effectively treat the severe stage of the disease due to a shift from a destructive to a static action mechanism, highlighting a need for drugs that actively kill the parasite.