Publications by authors named "R Khatami"

Article Synopsis
  • * Researchers analyzed data from over 1500 patients and found that women reported higher sleepiness on the Epworth Sleepiness Scale compared to men, with specific age-related trends observed in different patient groups.
  • * Notably, in women with narcoleptic conditions, an increase in daytime sleepiness was linked to age, while weight gain appeared later, suggesting a complex relationship that warrants further research for targeted treatment approaches.
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Article Synopsis
  • The study investigates the frequency of psychiatric disorders in patients with narcolepsy type-1 (NT1) and other central disorders of hypersomnolence (OCH), finding that 38 out of 90 patients (27% of NT1 and 48% of OCH) had at least one psychiatric issue.
  • Major depressive episodes and suicidality were the most common psychiatric conditions observed, with a notable prevalence among females.
  • Those with psychiatric comorbidities experienced more severe fatigue, apathy, disturbed sleep, and poorer overall quality of life, indicating a negative impact on their daily functioning due to the combination of these disorders and hypersomnolence symptoms.
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Article Synopsis
  • The Swiss Primary Hypersomnolence and Narcolepsy Cohort Study (SPHYNCS) aims to discover new biomarkers for central disorders of hypersomnolence, particularly focusing on narcolepsy type 1 (NT1) and its distinction from healthy controls.
  • Researchers used Fitbit smartwatches to gather data on physical activity, heart rate, and sleep over a year, achieving an impressive adherence rate of 80% among participants.
  • Findings revealed that NT1 patients showed increased sleep fragmentation and specific changes in sleep and heart rate metrics compared to healthy controls, indicating the potential for wearable technology to assist in the diagnosis and management of narcolepsy in the future.
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Article Synopsis
  • * Researchers reviewed medical records from 290 individuals with NT1 and 115 with NT2 or IH to analyze immunological events, such as infections and vaccinations, that occurred before the onset of hypersomnolence.
  • * Results indicate that NT1 shows a stronger association with flu infections and vaccinations, whereas NT2 and IH are linked to other viral infections; the study highlights the need for further investigation into these distinct immunological triggers.
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Objective: The aim of this study was to evaluate the impact of social support and religiosity/spirituality (R/S) on the recovery from an acute cardiac event or cardiac surgery during cardiac rehabilitation (CR).

Methods: In this prospective study, a convenience sample of 159 patients participating in a CR program were enrolled. Religiosity/spirituality, social support, anxiety, depression, health related quality of life (QoL), and exercise capacity (6-min walk test, cycle ergometer test) were assessed.

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