Past, present, and future of allergen immunotherapy vaccines.

Allergen-specific immunotherapy (AIT) is an allergen-specific form of treatment for patients suffering from immunoglobulin E (IgE)-associated allergy; the most common and important immunologically mediated hypersensitivity disease. AIT is based on the administration of the disease-causing allergen with the goal to induce a protective immunity consisting of allergen-specific blocking IgG antibodies and alterations of the cellular immune response so that the patient can tolerate allergen contact. Major advantages of AIT over all other existing treatments for allergy are that AIT induces a long-lasting protection and prevents the progression of disease to severe manifestations.

Expression and characterization of recombinant Par j 1 and Par j 2 resembling the allergenic epitopes of Parietaria judaica pollen.

The weed wall pellitory, Parietaria judaica, is one the most important pollen allergen sources in the Mediterranean area causing severe symptoms of hay fever and asthma in allergic patients. We report the expression of the major Parietaria allergens, Par j 1 and Par j 2 which belong to the family of lipid transfer proteins, in insect cells. According to circular dichroism analysis and gel filtration, the purified allergens represented folded and monomeric proteins.

[Consumption of carbohydratecontaining beverages and their contribution to the total calorie content of the diet].

The article presents data on the frequency of consumption of carbohydrate-containing sweet carbonated drinks by the population of the Russian Federation and their contribution to the overall caloric intake of the diet. Questioning 11 850 people of different ages (from 12 to 60 years) and sex in all eight Federal Districts of Russia has been conducted. The frequency of food consumption has been studied, and in parallel dietary intake has been assessed using 24-hour recall method.

[The structure of macronutrient consumption by the population of various regions of Russian Federation].

The article presents data on the consumption of macronutrients by the population of large cities of all eight Federal Districts of the Russian Federation. Dietary intake assessment was investigated using method of 24-hour recall. The analyzed sample consisted of 11 850 people.

[Features of nutrition of elderly patients with removable dental orthopedic constructions].

studying of features of nutrition in elderly patients with removable stomatologic orthopedic constructions. 1388 patients aged from 60 up to 75 years which addressed in a city dental out-patient department were examined. Patients were divided into three groups: group 1 - the persons having only fixed stomatologic orthopedic constructions (n=419); group 2 - the persons having at least one partially removable stomatologic orthopedic construction and not having full-removable orthopedic constructions (n=512); group 3 - the persons having at least one full-removable stomatologic orthopedic construction (n=457).