Rapunzel syndrome associated with trichotillomania and pica causing bowel obstruction in a 4 year-old-female: A rare case report from Nepal.

Introduction: Bezoars are an accumulation of human or vegetable fibers in the gastrointestinal tract which if extend to the small intestine are referred to as Rapunzel syndrome. They are primarily a psychiatric issue rather than a surgical condition and are associated with trichotillomania, with subsequent trichophagia, pica, and other psychiatric conditions usually seen in adolescent females. This case report describes an extremely rare diagnosis of Rapunzel syndrome in a 4-year-old female.

Therapeutic potential of : Chemical isolation and validation of ethnomedicinal claims through and assessment of antioxidant and anti-inflammatory properties.

(L.) Ridsdale has been used by different ethnic communities to manage diseased conditions that can be traced to oxidative stress and cellular inflammations but scientific evidences to support the claim are scanty. The objective of this study was to isolate and identify the antioxidants present in the aerial parts of perform their molecular docking against proteins to inspect whether the traditional uses of the plant can be validated by an in-silico approach.

Strengthening global health resilience: Marburg virus-like particle vaccines and the One Health approach.

The Marburg virus (MARV), belonging to the family, poses a significant global health threat, emphasizing the urgency to develop Marburg virus-like particle (VLP) vaccines for outbreak mitigation. The virus's menacing traits accentuate the need for such vaccines, which can be addressed by VLPs that mimic its structure safely, potentially overcoming past limitations. Early Marburg vaccine endeavors and their challenges are examined in the historical perspectives section, followed by an exploration of VLPs as transformative tools, capable of eliciting immune responses without conventional risks.

A Disaster Response Complex for training of emergency responders in the Northwest United States.

The Disaster Response Complex (DRC) is a year-round training complex that specializes in training emergency responders in realistic indoor and outdoor environments. The outdoor site is comprised of 3 acres of secured customizable space for various exercises. The indoor site is designed to include an indoor facility with a full-size city street, complete with storefronts and motor vehicles that can be configured for emergency response training exercises, and a train or subway station where mockups of derailments can be simulated.

Awareness of personal safety among frontline healthcare workers working in COVID ward of BPKIHS during COVID-19 pandemic: a cross-sectional study authors.

Background: Frontline healthcare workers are at higher risk for COVID-19 infection and due to lack of availability of adequate personal protective equipment (PPE), lack of knowledge and good practices results in more deaths each year due to occupational accidents and diseases.

Objective: The aim of the study was to assess the awareness of personal safety, the association between the level of awareness with selected socio-demographic variables and to identify the correlation between knowledge and practice of personal safety.

Materials And Methods: A descriptive cross-sectional study design was conducted among 106 Frontline Healthcare workers who have worked in the COVID ward.