Publications by authors named "R Kempker"
High Prescription Rate of Medications With Rifampin Drug-drug Interactions in Patients With Diabetic Foot Osteomyelitis: Should Rifabutin Be Included in Clinical Trials for Adjunctive Therapy?
Open Forum Infect Dis
November 2024
Article Synopsis
- Rifampin has potential benefits for treating diabetic foot osteomyelitis, but it has many drug interactions that could complicate its use.
- A study examined medications of 190 patients with this condition.
- The findings suggest that rifabutin, which has fewer interactions, could be a more practical alternative for treatment.
Objective: Antimicrobial resistance (AMR) renders many bacterial infections untreatable and results in substantial morbidity and mortality worldwide. Understanding antibiotic use in clinical settings including hospitals is critical to optimize antibiotic use and prevent resistance.
Design: Hospital antibiotic point prevalence survey (PPS).
Women from sub-Saharan Africa, including Ethiopia, are underrepresented in biomedical research due in part to limited access to high-quality research training and mentorship. Tuberculosis (TB) is a major public health problem in Ethiopia, with a limited number of female Ethiopian scientists engaged in TB-related research. To improve access to TB-related research training among junior women scientists, our NIH Fogarty International Center-funded D43 program released an all-women request for applications (RFA), which substantially increased the number of women applying for research training and the number of women trained in our program.
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- * Out of 1,032 participants, 3.3% died during treatment and 8.7% after, with a median death time of 21 months post-TB treatment, particularly within the first 3 years.
- * Those with HIV co-infection had a significantly higher risk of post-TB mortality (almost four times higher) compared to those without HIV, highlighting the need for better care for TB patients with comorbidities.
Introduction In low- and middle-income countries (LMICs), the availability of formal point-of-care ultrasound (POCUS) training remains limited, and there is limited data on how to train providers in these countries to use POCUS. This study aimed to describe a virtual training workshop for physicians in Ethiopia, with the intention of serving as a model that could guide similar initiatives. Methods The authors developed and implemented a three-day virtual workshop in 2022 for physicians in the Department of Medicine at Addis Ababa University in Ethiopia.
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